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How to Read COA and HPLC Reports

Tetrava Research Team5/20/20266 min read

A practical guide to interpreting purity and analytical outputs.

How to Read COA and HPLC Reports

A Certificate of Analysis (COA) confirms identity and purity for a specific batch. Look for batch number, test date, and reported purity percentage.

HPLC chromatograms show peak area for the target compound versus impurities. A single dominant peak near the expected retention time with minimal secondary peaks generally indicates higher purity.

Compare COA and HPLC documents together — COA summarizes acceptance criteria while HPLC provides the underlying chromatographic evidence.

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